Article
The prevalence of coeliac disease-associated human leukocyte antigens in South African transplant donors and recipients.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 5 Oct 2021
Mrubata K L, Barrow P, Mayne E, Nelson D, De Maayer T
Abstract excerpt
BACKGROUND: Coeliac disease (CD) is an autoimmune condition occurring in genetically predisposed individuals exposed to an environmental trigger. The human leukocyte antigen (HLA) haplotypes HLA-DQ2.5 and HLA-DQ8 have the strongest association with CD, and 90 - 95% of CD patients bear these haplotypes. The susceptibility of the South African (SA) population to CD has not been studied previously. OBJECTIVES: To...
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