Article
Frequencies of HLA-DQ2 and HLA-DQ8 haplotypes in Czech and Slovak coeliac patients and the healthy population.
Acta biochimica Polonica - 1 Jan 2014
Wroblova Katerina, Kolorz Michal, Pav Igor, Horakova Zuzana, Filipova Petra, Bartos Milan, Bartosova Ladislava
Abstract excerpt
Coeliac disease is an autoimmune disorder with genetic predisposition. The aim was to determine the frequency of HLA-DQ2 and HLA-DQ8 in Czech and Slovak patients and the healthy population. The study included 127 patients and 66 healthy volunteers. HLA-DQ2 was identified in 85.03% patients, and 24.24% healthy individuals (P=0.0001; OR17.7632; CI=8.4347-37.4088). HLA-DQ8 was identified in 11.81% patients and 15.5%...
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