Article
Coeliac Disease High-Risk Human Leukocyte Antigen Alleles in a South African Type One Diabetic Population.
Clinical laboratory - 1 Aug 2023
Gandini A, Wyk N Van, Maayer T De, Gededzha M P, Mayne E
Abstract excerpt
BACKGROUND: Coeliac disease (CD) is an autoimmune disorder strongly associated with Human Leukocyte Antigen (HLA) genes DQ2 and DQ8. These alleles are also associated with other autoimmune diseases including type 1 dia-betes (T1D) and these patients are consequently at a higher risk of developing CD. We examined the frequency of high-risk HLA alleles in a cohort of South African T1D pediatric patients. METHODS: A...
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