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Article

Primary Cilia Structure Is Prolonged in Enteric Neurons of 5xFAD Alzheimer's Disease Model Mice.

International journal of molecular sciences - 17 Dec 2021

Nguyen Vu Thu Thuy, Brücker Lena, Volz Ann-Kathrin, Baumgärtner Julia C, Dos Santos Guilherme Malena, Valeri Francesco, May-Simera Helen, Endres Kristina

Abstract excerpt

Neurodegenerative diseases such as Alzheimer's disease (AD) have long been acknowledged as mere disorders of the central nervous system (CNS). However, in recent years the gut with its autonomous nervous system and the multitude of microbial commensals has come into focus. Changes in gut properties have been described in patients and animal disease models such as altered enzyme secretion or architecture of the...

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Source

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Identifiers

PMID: 34948356
DOI: 10.3390/ijms222413564
PMCID: PMC8707868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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