Article
Association of FOXO3 Blood DNA Methylation with Cancer Risk, Cancer Survival, and Mortality.
Cells - 1 Dec 2021
Yu Chenglong, Hodge Allison M, Wong Ee Ming, Joo Jihoon Eric, Makalic Enes, Schmidt Daniel, Buchanan Daniel D, Hopper John L, Giles Graham G, Southey Melissa C, Dugué Pierre-Antoine
Abstract excerpt
Genetic variants in FOXO3 are associated with longevity. Here, we assessed whether blood DNA methylation at FOXO3 was associated with cancer risk, survival, and mortality. We used data from eight prospective case-control studies of breast (n = 409 cases), colorectal (n = 835), gastric (n = 170), kidney (n = 143), lung (n = 332), prostate (n = 869), and urothelial (n = 428) cancer and B-cell lymphoma (n = 438)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.