Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic and Epigenetic Targeting Therapy for Pediatric Acute Lymphoblastic Leukemia.

Cells - 29 Nov 2021

Xu Huan, Yu Hui, Jin Runming, Wu Xiaoyan, Chen Hongbo

Abstract excerpt

Acute lymphoblastic leukemia is the most common malignancy in children and is characterized by numerous genetic and epigenetic abnormalities. Epigenetic mechanisms, including DNA methylations and histone modifications, result in the heritable silencing of genes without a change in their coding sequence. Emerging studies are increasing our understanding of the epigenetic role of leukemogenesis and have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Lymphoblastic Leukemia research
Share to Child
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Histones

Share to Molecular Targeted Therapy

Share to Mutation

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Open in PubMed Open full text

Identifiers

PMID: 34943855
DOI: 10.3390/cells10123349
PMCID: PMC8699354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic and Epigenetic Targeting Therapy for Pediatric Acute Lymphoblastic Leukemia.PMID 34943855Read ↗

Epigenetic Modifications in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Epigenetic Modifications in Acute Lymphoblastic Leukemia: From Cellular Mechanisms to TherapeuticsSemantic proximity Read ↗

Epigenetics in pediatric acute lymphoblastic leukemiaSemantic proximity Read ↗

A Comprehensive Overview of Recent Advances in Epigenetics in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Epigenetic alterations in acute lymphoblastic leukemiaSemantic proximity Read ↗

Childhood acute lymphoblastic leukemia: Integrating genomics into therapy.Semantic proximity Read ↗

Biology of Childhood Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Genetic targets in pediatric acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetics and epigenetics of pediatric leukemia in the era of precision medicineSemantic proximity Read ↗

Novel Biomarkers and Molecular Targets in ALL.Semantic proximity Read ↗

Biology of childhood acute lymphoblastic leukemia.Semantic proximity Read ↗

Pharmacogenetics in acute lymphoblastic leukemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.