Article
Accelerated deciphering of the genetic architecture of agricultural economic traits in pigs using a low-coverage whole-genome sequencing strategy.
GigaScience - 20 Jul 2021
Yang Ruifei, Guo Xiaoli, Zhu Di, Tan Cheng, Bian Cheng, Ren Jiangli, Huang Zhuolin, Zhao Yiqiang, Cai Gengyuan, Liu Dewu, Wu Zhenfang, Wang Yuzhe, Li Ning, Hu Xiaoxiang
Abstract excerpt
BACKGROUND: Uncovering the genetic architecture of economic traits in pigs is important for agricultural breeding. However, high-density haplotype reference panels are unavailable in most agricultural species, limiting accurate genotype imputation in large populations. Moreover, the infinitesimal model of quantitative traits implies that weak association signals tend to be spread across most of the genome,...
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