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Article

EASINESS: E. coli Assisted Speedy affINity-maturation Evolution SyStem.

Frontiers in immunology - 1 Jan 2021

Zhang Hai-Nan, Xue Jun-Biao, Wang Aru Ze-Ling, Jiang He-Wei, Merugu Siva Bhararth, Li Da-Wei, Tao Sheng-Ce

Abstract excerpt

Antibodies are one of the most important groups of biomolecules for both clinical and basic research and have been developed as potential therapeutics. Affinity is the key feature for biological activity and clinical efficacy of an antibody, especially of therapeutic antibodies, and thus antibody affinity improvement is indispensable and still remains challenging. To address this issue, we developed the E. coli...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34925322
DOI: 10.3389/fimmu.2021.747267
PMCID: PMC8677947

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