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Article

Multidrug efflux pumps and their role in antibiotic and antiseptic resistance: a pharmacodynamic perspective

20 Oct 2016

Abstract excerpt

INTRODUCTION: Worrying levels of bacterial resistance have been reported worldwide involving the failure of many available antibiotic treatments. Multidrug resistance (MDR) in Gram-negative bacteria is often ascribed to the presence of multiple and different resistance mechanisms in the same strain. RND efflux pumps play a major role and are an attractive target to discover new antibacterial drugs. Areas covered:...

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PMID: 27764576
DOI: 10.1080/17425255.2017.1251581

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