Article
Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent behavior in C. elegans via a trans function.
Biochemical and biophysical research communications - 22 Jan 2022
Matúš Daniel, Post Willem Berend, Horn Susanne, Schöneberg Torsten, Prömel Simone
Abstract excerpt
Latrophilins are highly conserved Adhesion GPCRs playing essential roles in the mammalian nervous system and are associated with severe neurological disorders. Recently, it has been shown that murine Latrophilins mediate classical G-protein signals to drive synaptogenesis. However, there is evidence that Latrophilins in the nematode Caenorhabditis elegans can also function independently of their...
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