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Article

Ablation of mpeg+ Macrophages Exacerbates mfrp-Related Hyperopia.

Investigative ophthalmology & visual science - 1 Dec 2021

Brandt Zachary J, Collery Ross F, Besharse Joseph C, Link Brian A

Abstract excerpt

Purpose: Proper refractive development of the eye, termed emmetropization, is critical for focused vision and is impacted by both genetic determinants and several visual environment factors. Improper emmetropization caused by genetic variants can lead to congenital hyperopia, which is characterized by small eyes and relatively short ocular axial length. To date, variants in only four genes have been firmly...

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Identifiers

PMID: 34913948
DOI: 10.1167/iovs.62.15.13
PMCID: PMC8684298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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