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Article

Immune checkpoint inhibitor-related molecular markers predict prognosis in extrahepatic cholangiocarcinoma.

Cancer medicine - 1 Oct 2023

Jin Bao, Wang Yuxin, Zhang Baoluhe, Xu Haifeng, Lu Xin, Sang Xinting, Wang Wenze, Mao Yilei, Chen Pengxiao, Wang Shun, Qian Zhirong, Wang Yingyi, Du Shunda

Abstract excerpt

BACKGROUND: Therapeutic approaches for extrahepatic cholangiocarcinoma (EHCC) are limited, due to insufficient understanding to biomarkers related to prognosis and drug response. Here, we comprehensively assess the molecular characterization of EHCC with clinical implications. METHODS: Whole-exome sequencing (WES) on 37 tissue samples of EHCC were performed to evaluate genomic alterations, tumor mutational burden...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37814942
DOI: 10.1002/cam4.6441
PMCID: PMC10652350

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