Functional rare variant in a C/EBPbeta binding site in NINJ2 gene increases the risk of coronary artery disease.

doi:10.18632/aging.203755

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Article

Functional rare variant in a C/EBPbeta binding site in NINJ2 gene increases the risk of coronary artery disease.

Aging - 12 Dec 2021

Wang Pengyun, Wang Yifan, Peng Huixin, Wang Jingjing, Zheng Qian, Wang Pengxia, Wang Jing, Zhang Hongfu, Huang Yufeng, Xiong Liang, Zhang Rongfeng, Xia Yunlong, Wang Qing K, Xu Chengqi

Abstract excerpt

OBJECTIVE: NINJ2 regulates activation of vascular endothelial cells, and genome-wide association studies showed that variants in NINJ2 confer risk to stroke. However, whether variants in NINJ2 are associated with coronary artery disease (CAD) is unknown. METHODS: We genotyped rs34166160 in NINJ2 in two independent Chinese GeneID populations which included 2,794 CAD cases and 4,131 controls, and performed genetics...

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Identifiers

PMID: 34897030
DOI: 10.18632/aging.203755
PMCID: PMC8714150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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