Article
Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium.
PloS one - 1 Jan 2014
Bis Joshua C, DeStefano Anita, Liu Xiaoming, Brody Jennifer A, Choi Seung Hoan, Verhaaren Benjamin F J, Debette Stéphanie, Ikram M Arfan, Shahar Eyal, Butler Kenneth R, Gottesman Rebecca F, Muzny Donna, Kovar Christie L, Psaty Bruce M, Hofman Albert, Lumley Thomas, Gupta Mayetri, Wolf Philip A, van Duijn Cornelia, Gibbs Richard A, Mosley Thomas H, Longstreth W T, Boerwinkle Eric, Seshadri Sudha, Fornage Myriam
Abstract excerpt
BACKGROUND: Stroke, the leading neurologic cause of death and disability, has a substantial genetic component. We previously conducted a genome-wide association study (GWAS) in four prospective studies from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and demonstrated that sequence variants near the NINJ2 gene are associated with incident ischemic stroke. Here, we sought to...
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