Article
Whole-genome sequencing differentiates relapse from re-infection in TB.
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Dec 2021
Nikolenka A, Mansjö M, Skrahina A, Hurevich H, Grankov V, Nikisins S, Dara M, Ehsani S, Groenheit R
Abstract excerpt
BACKGROUND: Distinguishing TB relapse from re-infection is important from a clinical perspective to document transmission patterns. We investigated isolates from patients classified as relapse to understand if these were true relapses or re-infections. We also investigated shifts in drug susceptibility patterns to distinguish acquired drug resistance from re-infection with resistant strains.METHODS: Isolates from...
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