Article
Prevalence and temporal changes of mutations linked to antimalarial drug resistance in Plasmodium falciparum and Plasmodium vivax in Palawan, Philippines.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Mar 2022
Bareng Alison Paolo N, Grignard Lynn, Reyes Ralph, Fornace Kim, Spencer Freya, Macalinao Ma Lourdes, Luchavez Jennifer, Espino Fe Esperanza, Drakeley Chris, Hafalla Julius Clemence R
Abstract excerpt
OBJECTIVE: This study provides 2016 data on the prevalence of key single nucleotide polymorphisms (SNPs) associated with antimalarial drug resistance in Palawan, Philippines. Findings were combined with historical data to model temporal changes in the prevalence of these SNPs in Plasmodium isolates. METHODS: Plasmodium isolates were genotyped using drug resistance markers pfmdr1, pfcrt, pfdhfr, pfdhps, kelch-13,...
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