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Prevalence and dynamics of antimalarial drug resistance mutations among the Plasmodium falciparum isolates in TAK Province, Thailand, during the period of 1998-2001.

Antimicrobial agents and chemotherapy - 4 Sept 2024

Thaloengsok Sasikanya, Chaisatit Chaiyaporn, Saingam Piyaporn, Lertsethtakarn Paphavee, Spring Michele, Sriwichai Sabaithip, Pholwat Suporn, Guler Jennifer L, Houpt Eric R, Vesely Brian A

Abstract excerpt

Despite the overall decline in malaria cases in Thailand, continuous surveillance in endemic areas remains crucial. This retrospective analysis examined Plasmodium falciparum samples from Tak province, Thailand, collected in 1998, 1999, and 2001, to investigate the prevalence and evolution of antimalarial genotypic drug resistance. The study revealed a high prevalence of drug-resistant P. falciparum, particularly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39136466
DOI: 10.1128/aac.00779-24
PMCID: PMC11373219

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