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Comparative assessment of favipiravir and remdesivir against human coronavirus NL63 in molecular docking and cell culture models

6 Dec 2021

Abstract excerpt

Human coronavirus NL63 (HCoV-NL63) mainly affects young children and immunocompromised patients, causing morbidity and mortality in a subset of patients. Since no specific treatment is available, this study aims to explore the anti-SARS-CoV-2 agents including favipiravir and remdesivir for treating HCoV-NL63 infection. We first successfully modelled the 3D structure of HCoV-NL63 RNA-dependent RNA polymerase...

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PMID: 34873274
DOI: 10.1038/s41598-021-02972-y

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