Article
A profiling study of a newly developed HCVcc strain PR63cc's sensitivity to direct-acting antivirals.
Antiviral research - 1 Mar 2017
Tao Wanyin, Gan Tianyu, Lu Jie, Zhong Jin
Abstract excerpt
The development of direct-acting antivirals (DAAs) has significantly improved hepatitis C virus (HCV) treatment. However, drug resistance remains a potential concern in the real-world DAA-based therapies. We previously developed a novel full-length genotype 2a HCVcc clone PR63cc directly from clinical isolates. Here in this study, we compared the sensitivity of PR63cc and JFH1 to 12 different DAAs most of which...
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