Article
Systematic assembly of a full-length infectious clone of human coronavirus NL63.
Journal of virology - 1 Dec 2008
Donaldson Eric F, Yount Boyd, Sims Amy C, Burkett Susan, Pickles Raymond J, Baric Ralph S
Abstract excerpt
Historically, coronaviruses were predominantly associated with mild upper respiratory disease in humans. More recently, three novel coronaviruses associated with severe human respiratory disease were found, including (i) the severe acute respiratory syndrome coronavirus, associated with a significant atypical pneumonia and 10% mortality; (ii) HKU-1, associated with chronic pulmonary disease; and (iii) NL63,...
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