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Article

Identification of TRIM22 single nucleotide polymorphisms associated with loss of inhibition of HIV-1 transcription and advanced HIV-1 disease.

AIDS (London, England) - 24 Sept 2013

Ghezzi Silvia, Galli Laura, Kajaste-Rudnitski Anna, Turrini Filippo, Marelli Sara, Toniolo Daniela, Casoli Claudio, Riva Agostino, Poli Guido, Castagna Antonella, Vicenzi Elisa

Abstract excerpt

OBJECTIVE(S): Tripartite motif-containing 22 (TRIM22) is an interferon-induced protein that inhibits HIV-1 transcription and replication in vitro. Two single nucleotide missense polymorphisms rs7935564A/G (SNP-1) and rs1063303C/G (SNP-2) characterize the coding sequence of human TRIM22 gene. We tested whether these variants affected the inhibitory effect of TRIM22 on HIV-1 replication and transcription and their...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23921607
DOI: 10.1097/01.aids.0000432474.76873.5f

Genes

TRIM22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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