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Article

Analysis of the Expression and Prognostic Value of MSH2 in Pan-Cancer Based on Bioinformatics.

BioMed research international - 1 Jan 2021

Qiu Wenli, Ding Ke, Liao Lusheng, Ling Yongchang, Luo Xiaoqiong, Wang Junli

Abstract excerpt

BACKGROUND: MutS homolog 2 (MSH2), with the function of identifying mismatches and participating in DNA repair, is the "housekeeping gene" in the mismatch repair (MMR) system. MSH2 deficiency has been reported to enhance cancer susceptibility for the association of hereditary nonpolyposis colorectal cancer. However, the expression and prognostic significance of MSH2 have not been studied from the perspective of...

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Identifiers

PMID: 34859104
DOI: 10.1155/2021/9485273
PMCID: PMC8632401

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