Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causality between coffee intake and bone health: A Mendelian randomization study.

Medicine - 12 Sept 2025

Yang Heng, Yang Liling, Li Zongping, Liu Hongyuan

Abstract excerpt

Observational studies have reported associations between coffee intake and osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP). However, it remains unknown whether these relationships are causal. In this study, we applied a 2-sample bidirectional Mendelian randomization (MR) analysis to comprehensively evaluate the causal association between coffee intake and OA, RA, and OP. Genetic data for OA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Causality
Share to Coffee

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Datasets as Topic

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Osteoarthritis

Share to Osteoporosis

Source

Open in PubMed Open full text

Identifiers

PMID: 40958293
DOI: 10.1097/MD.0000000000044533
PMCID: PMC12440504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causality between coffee intake and bone health: A Mendelian randomization study.PMID 40958293Read ↗

The effect of coffee consumption on three main bone disorders: a Mendelian randomization trial.Semantic proximity Read ↗

Self-reported and genetically predicted effects of coffee intake on rheumatoid arthritis: Epidemiological studies and Mendelian randomization analysisSemantic proximity Read ↗

Causal Factors for Osteoarthritis: A Scoping Review of Mendelian Randomization Studies.Semantic proximity Read ↗

Causal Association of Coffee Consumption and Total, Knee, Hip and Self-Reported Osteoarthritis: A Mendelian Randomization Study.Semantic proximity Read ↗

Investigating the possible causal association of coffee consumption with osteoarthritis risk using a Mendelian randomization analysis.Semantic proximity Read ↗

Causal Associations of Circulating Lipids with Osteoarthritis: A Bidirectional Mendelian Randomization Study.Semantic proximity Read ↗

Coffee consumption and the risk of rheumatoid arthritis and systemic lupus erythematosus: a Mendelian randomization study.Semantic proximity Read ↗

Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysisSemantic proximity Read ↗

Causal factors for osteoarthritis risk revealed by mendelian randomization analysis.Semantic proximity Read ↗

Association between habitual coffee consumption and multiple disease outcomes: A Mendelian randomisation phenome-wide association study in the UK Biobank.Semantic proximity Read ↗

Mendelian Randomization Studies of Coffee and Caffeine ConsumptionSemantic proximity Read ↗

The Causal Association between Alcohol, Smoking, Coffee Consumption, and the Risk of Arthritis: A Meta-Analysis of Mendelian Randomization Studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.