Article
Tumor Mutational Burden as a Biomarker for Advanced Biliary Tract Cancer.
Technology in cancer research & treatment - 1 Jan 2000
Kim Hongsik, Kim Hana, Kim Ryul, Jo Hyunji, Kim Hye Ryeon, Hong Joohyun, Park Joon Oh, Park Young Suk, Kim Seung Tae
Abstract excerpt
Background: High tumor mutational burden (TMB-H) has been reported as a predictive marker to immunotherapy or prognostic marker in various tumor types. However, there has been little study of the role of TMB-H in advanced biliary tract cancer (BTC). Methods: We analyzed 119 advanced BTC patients who received Gemcitabine/Cisplatin (GP) as a first-line treatment between November 2019 and April 2021. Next-generation...
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