Development of a custom next-generation sequencing panel for the determination of bladder cancer risk in a Tunisian cohort.

doi:10.1007/s11033-021-06951-4

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Development of a custom next-generation sequencing panel for the determination of bladder cancer risk in a Tunisian cohort.

Molecular biology reports - 1 Feb 2022

Hemissi Imen, Boussetta Sami, Dallali Hamza, Hellal Faycel, Durand Geoffroy, Voegele Catherine, Ayed Haroun, Zaghbib Selim, Naimi Zeineb, Ayadi Mouna, Chebil Mohamed, Mckay James, Le Calvez-Kelm Florence, Ouerhani Slah

Abstract excerpt

BACKGOUND: Bladder cancer (BCa) is a heterogeneous disease caused by the interaction between environmental and genetic risk factors. The goal of this case-control study was to evaluate the implication of a selected SNP panel in the risk of BCa development in a Tunisian cohort. We were also interested in studying the interaction between this predictive panel and environmental risk factors. METHODS: The...

Topics

Aged
Aged, 80 and over
Case-Control Studies
Cohort Studies
Female
Gene Expression
Gene Expression Profiling
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Testing

Genotype

High-Throughput Nucleotide Sequencing

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Risk Factors

Transcriptome

Source

Open in PubMed

Identifiers

PMID: 34854013
DOI: 10.1007/s11033-021-06951-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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