Article
Identification of potential therapeutic targets in urothelial bladder carcinoma of Chinese population by targeted next-generation sequencing.
Cancer biology & therapy - 2 Aug 2020
Wang Tao, Liu Zhengsheng, Wang Xuegang, Bai Peide, Sun Anran, Shao Zhiqiang, Luo Rongtuan, Wu Zhun, Zhang Kaiyan, Li Wei, Xiao Wen, Duan Bo, Wang Yongfeng, Chen Bin, Xing Jinchun
Abstract excerpt
Patients with urothelial carcinoma (UC) of the bladder have a high risk of death in China. However, a lack of comprehensive molecular profiling in Chinese Han population hinders the development of targeted therapies for bladder cancer. In our present study, we collected fresh bladder tumors from low-grade (T1, N0, M0, G1) non-muscle invasive bladder cancer (NMIBC) patients (n = 16) and high-grade (T2-4, N0, M0,...
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