Article
Sickle cell disease patients in two London trusts: Genotyping including RH variants.
Transfusion medicine (Oxford, England) - 1 Jun 2022
Hui Yee Man Tracy, Gurung Kamala, Layton David Mark, Ibidapo Mercy, Grimsley Shane, Regan Fiona
Abstract excerpt
BACKGROUND: All SCD patients need extended RBC antigen typing (by serology or genotyping) for provision of extended RH, K matched blood and to guide RBC selection in those with complex transfusion requirements. Genotyping can also identify RH variants which can cause sensitisation even when extended RH phenotypically matched blood is provided and alloantibodies associated with RH variants can cause HTRs....
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