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An improved auxin-inducible degron system for fission yeast.

G3 (Bethesda, Md.) - 4 Jan 2022

Zhang Xiao-Ran, Zhao Lei, Suo Fang, Gao Yadong, Wu Qingcui, Qi Xiangbing, Du Li-Lin

Abstract excerpt

Conditional degron technologies, which allow a protein of interest to be degraded in an inducible manner, are important tools for biological research, and are especially useful for creating conditional loss-of-function mutants of essential genes. The auxin-inducible degron (AID) technology, which utilizes plant auxin signaling components to control protein degradation in nonplant species, is a widely used...

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PMID: 34849776
DOI: 10.1093/g3journal/jkab393
PMCID: PMC8727963

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