Article
Branched-chain amino acids govern the high learning ability phenotype in Tokai high avoider (THA) rats.
Scientific reports - 29 Nov 2021
Shida Yukari, Endo Hitoshi, Owada Satoshi, Inagaki Yutaka, Sumiyoshi Hideaki, Kamiya Akihide, Eto Tomoo, Tatemichi Masayuki
Abstract excerpt
To fully understand the mechanisms governing learning and memory, animal models with minor interindividual variability and higher cognitive function are required. THA rats established by crossing those with high learning capacity exhibit excellent learning and memory abilities, but the factors underlying their phenotype are completely unknown. In the current study, we compare the hippocampi of parental strain...
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