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Genetics of prostate cancer and its utility in treatment and screening.

Advances in genetics - 1 Jan 2021

Benafif S, Ni Raghallaigh H, McHugh J, Eeles R

Abstract excerpt

Prostate cancer heritability is attributed to a combination of rare, moderate to highly penetrant genetic variants as well as commonly occurring variants conferring modest risks [single nucleotide polymorphisms (SNPs)]. Some of the former type of variants (e.g., BRCA2 mutations) predispose particularly to aggressive prostate cancer and confer poorer prognoses compared to men who do not carry mutations....

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Identifiers

PMID: 34844712
DOI: 10.1016/bs.adgen.2021.08.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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