Article
MicroRNA expression and JAK2 allele burden in bone marrow trephine biopsies of polycythemia vera, essential thrombocythemia and early primary myelofibrosis.
Acta haematologica - 1 Jan 2013
Gebauer Niklas, Bernard Veronica, Gebauer Wolfgang, Feller Alfred C, Merz Hartmut
Abstract excerpt
BACKGROUND/AIMS: MicroRNAs (miRNAs) play an important role in cellular differentiation and cancer pathogenesis. However, their role in promoting the malignant phenotype of myeloproliferative diseases and their importance for differential diagnosis of early-stage chronic myeloproliferative diseases (CMPDs) remains widely obscure. METHODS: In this study, we systematically evaluated the differential expression of...
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