Article
Molecular pathology of the basement membrane zone in heritable blistering diseases:: The paradigm of epidermolysis bullosa.
Matrix biology : journal of the International Society for Matrix Biology - 1 Jan 2017
Uitto Jouni, Has Cristina, Vahidnezhad Hassan, Youssefian Leila, Bruckner-Tuderman Leena
Abstract excerpt
Epidermolysis bullosa (EB), a phenotypically heterogeneous group of skin fragility disorders, is characterized by blistering and erosions with considerable morbidity and mortality. Mutations in as many as 18 distinct genes expressed at the cutaneous basement membrane zone have been shown to be associated with the blistering phenotype, attesting to the role of the corresponding proteins in providing stable...
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