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Changes in intestinal barrier protein expression and intestinal flora in a rat model of visceral hypersensitivity

25 Nov 2021

Abstract excerpt

BACKGROUND: Destruction of the intestinal mucosal barrier and visceral hypersensitivity are main pathogenesis of irritable bowel syndrome (IBS). The study aimed to establish a rat model of visceral hypersensitivity and explore mechanisms involved the changes of the intestinal barrier protein expression and intestinal flora. METHODS: A rat model of visceral hypersensitivity was established and evaluated using...

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PMID: 34821442
DOI: 10.1111/nmo.14299

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