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Article

UBE2E3 regulates cellular senescence and osteogenic differentiation of BMSCs during aging

18 Nov 2021

Abstract excerpt

Background Osteoporosis has gradually become a public health problem in the world. However, the exact molecular mechanism of osteoporosis still remains unclear. Senescence and osteogenic differentiation inhibition of bone marrow mesenchymal stem cells (BMSCs ) are supposed to play an important part in osteoporosis. Methods We used two gene expression profiles ( GSE35956 and GSE35958 ) associated with osteoporosis...

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Share to Bone Metabolism and Diseases
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PMID: 34820159
DOI: 10.7717/peerj.12253

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