Article
Tag Variants of LGALS-3 Containing Haplotype Block in Advanced Carotid Atherosclerosis.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jan 2022
Djordjevic Ana, Zivkovic Maja, Koncar Igor, Stankovic Aleksandra, Kuveljic Jovana, Djuric Tamara
Abstract excerpt
OBJECTIVES: Galectin-3 affects a variety of biological processes. It is encoded by LGALS-3, located in unique haplotype block in Caucasians. Most of the studies regarding the gal-3 role in atherosclerosis are focused exclusively on protein/mRNA levels. Genetic analyses of LGALS-3 are scarce. We sought to thoroughly examine the genetic background of gal-3 and to analyze tag variants that cover more than 80%...
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