Sertoli cells are the target of environmental toxicants in the testis – a mechanistic and therapeutic insight

Abstract excerpt

INTRODUCTION: Sertoli cells support germ cell development in the testis via an elaborate network of cell junctions that confers structural, communicating, and signaling support. However, Sertoli cell junctions and cytoskeletons are the target of environmental toxicants. Because germ cells rely on Sertoli cells for the provision of structural/functional/nutritional support, exposure of males to toxicants leads to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Male Reproductive Health Studies
• Share to Sperm and Testicular Function
• Share to Testicular diseases and treatments