Article
Two single mutations in carboxylesterase 001C improve fenvalerate hydrolase activity in Helicoverpa armigera.
Pesticide biochemistry and physiology - 1 Nov 2021
Xu Jing-Jing, Chang Yong-Mei, Lu Mei, Tie Yuan, Dong Yan-Ling, Chen Guang-You, Ma Zhi-Qing, Liu Xi-Li, Li Yong-Qiang
Abstract excerpt
Carboxylesterases (CarEs) usually play critical roles in the detoxification of toxic chemicals and therefore may be involved in insecticide resistance in agricultural pests. Previous work has shown that CarE 001C from Helicoverpa armigera was able to metabolize the isomers of cypermethrin and fenvalerate. In this study, seven mutants of CarE 001C with single amino acid substitution were produced and expressed in...
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