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Development and evaluation of a hybrid capture-based NGS panel for comprehensive detection of respiratory pathogens

26 Nov 2025

Abstract excerpt

Infectious diseases caused by diverse pathogens-including viruses, bacteria, and fungi-pose a significant diagnostic challenge, especially when conventional assays fail to identify the causative agents. Next-generation sequencing (NGS), particularly hybrid-capture-based NGS, offers a culture-independent approach for comprehensive pathogen detection directly from clinical samples. In this study, we developed a...

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PMID: 41298814
DOI: 10.1038/s41598-025-26421-2

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