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1 H, 15 N and 13 C resonance assignments of the Q61H mutant of human KRAS bound to GDP.

Biomolecular NMR assignments - 1 Apr 2022

Huang Qiwei, Ng Elizabeth Yihui, Li Qingxin, Kang CongBao

Abstract excerpt

KRAS proteins are small GTPases binding to the cell membrane and playing important roles in signal transduction. KRAS proteins form complexes with GTP and GDP to result in active and inactive conformations favouring interactions with different proteins. Mutations in KRAS have impact on the GTPase activity and some mutants are related to certain types of cancers. In addition to mutation at position 12, the Q61H...

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PMID: 34787842
DOI: 10.1007/s12104-021-10058-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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