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Article

Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer

11 Nov 2021

Abstract excerpt

Colorectal cancer (CRC) incidence in young adults is rising. Identifying genetic risk factors is fundamental for the clinical management of patients and their families. This study aimed to identify clinically significant germline variants among young adults with CRC. Whole-exome sequencing data of blood-derived DNA from 133 unrelated young CRC patients (<55 years of age) underwent a comprehensive analysis of 133...

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PMID: 34761457
DOI: 10.1002/gcc.23011

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