Article
Mutations in the osteoprotegerin-encoding gene are associated with temporomandibular joint ankylosis.
Oral surgery, oral medicine, oral pathology and oral radiology - 1 Mar 2022
Corso Paola Fernanda, Machado Renato Assis, Gerber Jennifer Tsi, Deliberador Tatiana Miranda, Costa Davani Latarullo, Klüppel Leandro Eduardo, Rebellato Nelson Luis Barbosa, Brancher João Armando, Küchler Erika Calvano, Coletta Ricardo D, Scariot Rafaela
Abstract excerpt
OBJECTIVE: This study aimed to investigate genetic variations in the osteoprotegerin-encoding gene (TNFRSF11B) in patients with temporomandibular joint ankylosis (TMJA). STUDY DESIGN: The sample comprised 17 patients diagnosed with TMJA, of both sexes with ages ranging from 6 to 57 years old. TNFRSF11B mutational analysis was performed using the Sanger sequencing method with DNA extracted from oral cells, and the...
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