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Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells

1 Mar 2019

Abstract excerpt

ABSTRACT Kidney organoids have potential uses in disease modelling, drug screening and regenerative medicine. However, novel cost-effective techniques are needed to enable scaled-up production of kidney cell types in vitro. We describe here a modified suspension culture method for the generation of kidney micro-organoids from human pluripotent stem cells. Optimisation of differentiation conditions allowed the...

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PMID: 30846463
DOI: 10.1242/dev.172361

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