Article
Association between the IL17RA rs4819554 polymorphism and reduced renal filtration rate in the Spanish RENASTUR cohort.
Human immunology - 1 Mar 2015
Coto Eliecer, Gómez Juan, Suárez Beatriz, Tranche Salvador, Díaz-Corte Carmen, Ortiz Alberto, Ruiz-Ortega Marta, Coto-Segura Pablo, Batalla Ana, López-Larrea Carlos
Abstract excerpt
DNA variants at the genes that encode components of the IL17-pathway may contribute to the risk of impaired renal function/chronic kidney disease. Our aim was to determine whether common IL17RA single nucleotide polymorphisms (SNPs) were associated with a reduced estimated glomerular filtration rate (eGFR) in a cohort of healthy elderly individuals (n=650). We found a significantly higher frequency of SNP...
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