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Article

The role of uspE in virulence and biofilm formation by Histophilus somni.

Veterinary microbiology - 1 Dec 2021

Pan Yu, Subhadra Bindu, Sandal Indra, Dickerman Allan, Inzana Thomas J

Abstract excerpt

UspE is a global regulator in Escherichia coli. To study the function of Histophilus somni uspE, strain 2336::TnuspE was identified from a bank of mutants generated with EZ::Tn5™<KAN-2> Tnp Transposome™ that were biofilm deficient. The 2336::TnuspE mutant was highly attenuated in mice, the electrophoretic profile of its lipooligosaccharide (LOS) indicated the LOS was truncated, and the mutant was significantly...

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Identifiers

PMID: 34739965
DOI: 10.1016/j.vetmic.2021.109267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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