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Article

The Role of luxS in Histophilus somni Virulence and Biofilm Formation.

Infection and immunity - 19 Jan 2021

Pan Yu, Siddaramappa Shivakumara, Sandal Indra, Dickerman Allan, Bandara Aloka B, Inzana Thomas J

Abstract excerpt

S-Ribosylhomocysteinase (LuxS) is required for the synthesis of the autoinducer-2 (AI-2) quorum-sensing signaling molecule in many Gram-negative bacteria. The bovine (and ovine) opportunistic pathogen Histophilus somni contains luxS and forms a biofilm containing an exopolysaccharide (EPS) in the matrix. Since biofilm formation is regulated by quorum sensing in many bacteria, the roles of luxS in H. somni...

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Identifiers

PMID: 33139386
DOI: 10.1128/IAI.00567-20
PMCID: PMC7822144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The Role of luxS in Histophilus somni Virulence and Biofilm Formation.PMID 33139386Read ↗

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