Article
Association of cytokine gene polymorphisms and serum concentrations with the outcome of chronic hepatitis B.
Cytokine - 1 Mar 2013
Conde Simone R S, Feitosa Rosimar N M, Freitas Felipe Bonfim, Hermes Renata B, Demachki Samia, Araújo Marialva T F, Soares Manoel C P, Ishak Ricardo, Vallinoto Antonio C R
Abstract excerpt
OBJECTIVE: The present paper investigated possible correlations between the clinical presentation of hepatitis B and the TNF-α -308G/A, IFN-γ +874A/T, TGF-beta1 -509C/T, and IL-10 -1081A/G polymorphisms and associated serum levels of these cytokines. METHODS: Fifty-three hepatitis patients were selected and divided into two groups: A - inactive (n=30) and B - chronic hepatitis/cirrhosis (n=23). The control group...
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