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Article

Association of tumor mutational burden with genomic alterations in Chinese urothelial carcinoma.

Molecular carcinogenesis - 1 Mar 2022

Chen Xusheng, Ou Zhenyu, Wang Lei, Zhang Zhenting, Fan Xiaodong, Liu Huanhuan, Wang Wenping, Zhang Yanrui, Zhu Jun, Liang Xiayuan, Lou Feng, Cao Shanbo, Yao Ye, Wang Huina, Yao Xin

Abstract excerpt

The tumor mutational burden (TMB) calculated by whole-exome sequencing (WES) is a promising biomarker for the response to immune checkpoint inhibition (ICIs) in solid tumors. However, WES is not feasible in the routine clinical setting. In addition, the characteristics of the TMB in Chinese urothelial carcinoma (UC) are unclear. The aim of this study was to demonstrate the reliability of an Acornmed 808 panel and...

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PMID: 34729830
DOI: 10.1002/mc.23368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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