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An Accurate and Comprehensive Clinical Sequencing Assay for Cancer Targeted and Immunotherapies

13 Aug 2019

Abstract excerpt

Abstract Background Incorporation of next-generation sequencing (NGS) technology into clinical utility in targeted and immunotherapies requires stringent validation, including the assessment of tumor mutational burden (TMB) and microsatellite instability (MSI) status by NGS as important biomarkers for response to immune checkpoint inhibitors. Materials and Methods We designed an NGS assay, Cancer Sequencing YS...

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PMID: 31409745
DOI: 10.1634/theoncologist.2019-0236

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