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Article

Weighted gene co-expression network analysis to identify key modules and hub genes associated with paucigranulocytic asthma.

BMC pulmonary medicine - 2 Nov 2021

Li Min, Zhu Wenye, Wang Chu, Zheng Yuanyuan, Sun Shibo, Fang Yan, Luo Zhuang

Abstract excerpt

BACKGROUND: Asthma is a heterogeneous disease that can be divided into four inflammatory phenotypes: eosinophilic asthma (EA), neutrophilic asthma (NA), mixed granulocytic asthma (MGA), and paucigranulocytic asthma (PGA). While research has mainly focused on EA and NA, the understanding of PGA is limited. In this study, we aimed to identify underlying mechanisms and hub genes of PGA. METHODS: Based on the dataset...

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Identifiers

PMID: 34727921
DOI: 10.1186/s12890-021-01711-3
PMCID: PMC8565058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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