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Article

The use of biomarkers and HPV genotyping to improve diagnostic accuracy in women with a transformation zone type 3.

British journal of cancer - 1 Jan 2022

Manley Kristyn, Patel Amit, Pawade Joya, Glew Susan, Hunt Katherine, Villeneuve Nichole, Mukonoweshuro Pinias, Thompson Samantha, Hoskins Helen, López-Bernal Andres, Wills Andrew

Abstract excerpt

BACKGROUND: Twenty percent of women referred to colposcopy have a type 3 transformation zone-where colposcopic assessment for high-grade dysplasia (CIN2+) is not possible. This study examines the effectiveness of HPV biomarkers and genotyping in combination with techniques that sample an endocervical TZ. METHODS: A prospective diagnostic accuracy study. Women booked for large-loop excision (LLETZ) with squamous...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34716397
DOI: 10.1038/s41416-021-01539-y
PMCID: PMC8727619

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